Chuck Lorre may be the busiest reigning sitcom creator on TV, with two hit shows in “Two and a Half Men” and “The Big Bang Theory” and a third comedy coming this fall in “Mike & Molly.”

But Lorre, who was also behind “Dharma & Greg,” Roseanne” and “Grace Under Fire,” lives in fear that despite the success he’s achieved it could all fall apart with one bad episodes.

“The relationship with the audience, I
 have always believed, is so fragile,” Lorre told the first of two consecutive sessions at the TV Critics Press Tour Wednesday, “You have to think in terms 
of every episode being everything you can bring to it to 
make it.”

There’s too much competition with TV in general, Lorre says. “There’s too many things for people to do.
There’s too many choices.”


Though “Big Bang Theory” became a bona fide hit in its third season, it’s worrisome for him that it’s being moved from Monday’s to the more competitive Thursdays at 8 p.m.

“It’s almost like a 
relaunch of the show, establishing it,” he says. “It feels entirely like a do-over in a way. So we are really doing
 everything we can to make it everything we believe it
should be.”

Lorre says he can’t think in terms of future seasons because every one of his sitcoms is “one episode at a time. It’s impossible 
to think long-term because the pressing concerns is the
script that you are shooting now or the script that you
are writing now, the scene that’s not working, the jokes
that aren’t funny, fix that, make that better, we are
 running out of time, the audience isn’t laughing, do 
something. There’s no way to think down the road. And I
 guess that’s a blessing because the focus is on what’s
 right in front of you, and that’s the show we are
 shooting right now, which we are working on the show we
are going to shoot next week.”

Even on the hit “Two and a Half Men” which seems like it was unaffected by star Charlie Sheen’s domestic violence conviction, as it enters its eighth season, is a big hit. But even it doesn’t run itself, Lorre says.

“Everybody on that show 
works their asses off to make it a great show. And it
 doesn’t matter that it’s the eighth season. It’s still — we’re one show
away from losing the audience, really, every week…

“It’s a very fragile
relationship. Every episode has to be one worth
watching.”

“Mike & Molly” is the third sitcom he’s throwing into the mix, about two large people who meet at an Overeaters Anonymous meeting. But all of his shows share a common theme, Lorre says.

“I’ve felt for a long time that all shows
really, especially comedies,” he says, are “fundamentally family shows. “Even
people in an office create a surrogate family. You
know, the characters in ‘Taxi,’ they were a family,
 the characters in ‘Cheers.’ They operated as a
 family. They supported each other. They knocked each
other down.

They were inseparable in some ways. They
 made each other miserable. They functioned in all
 those ways that we experience as family.

“And I think 
hopefully if we get it right, this is a new family to 
be part of and to watch,” he says of “Mike & Molly.” “If 
we get it right, these shows are about the family.”